Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | KCNMA1 |
|---|---|
| DrugBank ID | DB00356 |
| Drug Name | Chlorzoxazone |
| Target ID | BE0000553 |
| UniProt ID | Q12791 |
| Regulation Type | |
| PubMed IDs | 16859676; 20505091; 10712246 |
| Citations | Dong DL, Luan Y, Feng TM, Fan CL, Yue P, Sun ZJ, Gu RM, Yang BF: Chlorzoxazone inhibits contraction of rat thoracic aorta. Eur J Pharmacol. 2006 Sep 18;545(2-3):161-6. Epub 2006 Jun 29.@@Alvina K, Khodakhah K: KCa channels as therapeutic targets in episodic ataxia type-2. J Neurosci. 2010 May 26;30(21):7249-57. doi: 10.1523/JNEUROSCI.6341-09.2010.@@Syme CA, Gerlach AC, Singh AK, Devor DC: Pharmacological activation of cloned intermediate- and small-conductance Ca(2+)-activated K(+) channels. Am J Physiol Cell Physiol. 2000 Mar;278(3):C570-81. |
| Groups | Approved |
| Direct Classification | Benzoxazolones |
| SMILES | ClC1=CC2=C(OC(=O)N2)C=C1 |
| Pathways | |
| PharmGKB | PA448971 |
| ChEMBL | CHEMBL1371 |
