Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30084718HIVENSG00000135480.17protein_codingKRT7NoNo3855P08729
TVIS20013646HPVENSG00000135480.17protein_codingKRT7NoNo3855P08729
TCGA Plot Options
Drug Information
GeneKRT7
DrugBank IDDB01087
Drug NamePrimaquine
Target IDBE0002459
UniProt IDP08729
Regulation Typeother/unknown
PubMed IDs12711178; 20713019
CitationsHeard CM, Monk BV, Modley AJ: Binding of primaquine to epidermal membranes and keratin. Int J Pharm. 2003 May 12;257(1-2):237-44.@@Basso LG, Rodrigues RZ, Naal RM, Costa-Filho AJ: Effects of the antimalarial drug primaquine on the dynamic structure of lipid model membranes. Biochim Biophys Acta. 2011 Jan;1808(1):55-64. doi: 10.1016/j.bbamem.2010.08.009. Epub 2010 Aug 14.
GroupsApproved
Direct ClassificationAminoquinolines and derivatives
SMILESCOC1=CC(NC(C)CCCN)=C2N=CC=CC2=C1
Pathways
PharmGKBPA451103
ChEMBLCHEMBL506