| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30084718 | HIV | ENSG00000135480.17 | protein_coding | KRT7 | No | No | 3855 | P08729 |
| TVIS20013646 | HPV | ENSG00000135480.17 | protein_coding | KRT7 | No | No | 3855 | P08729 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | KRT7 |
|---|---|
| DrugBank ID | DB01087 |
| Drug Name | Primaquine |
| Target ID | BE0002459 |
| UniProt ID | P08729 |
| Regulation Type | other/unknown |
| PubMed IDs | 12711178; 20713019 |
| Citations | Heard CM, Monk BV, Modley AJ: Binding of primaquine to epidermal membranes and keratin. Int J Pharm. 2003 May 12;257(1-2):237-44.@@Basso LG, Rodrigues RZ, Naal RM, Costa-Filho AJ: Effects of the antimalarial drug primaquine on the dynamic structure of lipid model membranes. Biochim Biophys Acta. 2011 Jan;1808(1):55-64. doi: 10.1016/j.bbamem.2010.08.009. Epub 2010 Aug 14. |
| Groups | Approved |
| Direct Classification | Aminoquinolines and derivatives |
| SMILES | COC1=CC(NC(C)CCCN)=C2N=CC=CC2=C1 |
| Pathways | |
| PharmGKB | PA451103 |
| ChEMBL | CHEMBL506 |