| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30051254 | HIV | ENSG00000169967.17 | protein_coding | MAP3K2 | No | No | 10746 | Q9Y2U5 |
| TVIS30051255 | HIV | ENSG00000169967.17 | protein_coding | MAP3K2 | No | No | 10746 | Q9Y2U5 |
| TVIS30051256 | HIV | ENSG00000169967.17 | protein_coding | MAP3K2 | No | No | 10746 | Q9Y2U5 |
| TVIS30051257 | HIV | ENSG00000169967.17 | protein_coding | MAP3K2 | No | No | 10746 | Q9Y2U5 |
| TVIS30051258 | HIV | ENSG00000169967.17 | protein_coding | MAP3K2 | No | No | 10746 | Q9Y2U5 |
| TVIS20039087 | HPV | ENSG00000169967.17 | protein_coding | MAP3K2 | No | No | 10746 | Q9Y2U5 |
| TVIS20038057 | HPV | ENSG00000169967.17 | protein_coding | MAP3K2 | No | No | 10746 | Q9Y2U5 |
| TVIS44007281 | HTLV-1 | ENSG00000169967.17 | protein_coding | MAP3K2 | No | No | 10746 | Q9Y2U5 |
| TVIS44033535 | HTLV-1 | ENSG00000169967.17 | protein_coding | MAP3K2 | No | No | 10746 | Q9Y2U5 |
| TVIS44033592 | HTLV-1 | ENSG00000169967.17 | protein_coding | MAP3K2 | No | No | 10746 | Q9Y2U5 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | MAP3K2 |
|---|---|
| DrugBank ID | DB06616 |
| Drug Name | Bosutinib |
| Target ID | BE0004745 |
| UniProt ID | Q9Y2U5 |
| Regulation Type | inhibitor |
| PubMed IDs | 23134735 |
| Citations | Ahmad S, Hughes MA, Johnson GL, Scott JE: Development and validation of a high-throughput intrinsic ATPase activity assay for the discovery of MEKK2 inhibitors. J Biomol Screen. 2013 Apr;18(4):388-99. doi: 10.1177/1087057112466430. Epub 2012 Nov 7. |
| Groups | Approved |
| Direct Classification | 4-aminoquinolines |
| SMILES | COC1=CC(NC2=C(C=NC3=CC(OCCCN4CCN(C)CC4)=C(OC)C=C23)C#N)=C(Cl)C=C1Cl |
| Pathways | Bosutinib Inhibition of BCR-ABL |
| PharmGKB | |
| ChEMBL | CHEMBL288441 |
