Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10037130HBVENSG00000118113.12protein_codingMMP8NoNo4317P22894
TVIS30087721HIVENSG00000118113.12protein_codingMMP8NoNo4317P22894
TCGA Plot Options
Drug Information
GeneMMP8
DrugBank IDDB00786
Drug NameMarimastat
Target IDBE0001182
UniProt IDP22894
Regulation Typeinhibitor
PubMed IDs10852638; 10669951
CitationsHeath EI, Grochow LB: Clinical potential of matrix metalloprotease inhibitors in cancer therapy. Drugs. 2000 May;59(5):1043-55.@@Belotti D, Paganoni P, Giavazzi R: MMP inhibitors: experimental and clinical studies. Int J Biol Markers. 1999 Oct-Dec;14(4):232-8.
GroupsInvestigational
Direct ClassificationSecondary alcohols
SMILESCNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](O)C(=O)NO)C(C)(C)C
Pathways
PharmGKBPA164748329
ChEMBLCHEMBL279785