| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10017714 | HBV | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
| TVIS10015036 | HBV | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
| TVIS10030720 | HBV | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
| TVIS10035479 | HBV | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
| TVIS10018975 | HBV | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
| TVIS10049265 | HBV | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
| TVIS20002315 | HPV | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
| TVIS44045260 | HTLV-1 | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
| TVIS44045289 | HTLV-1 | ENSG00000122194.20 | protein_coding | PLG | No | No | 5340 | P00747 Q5TEH5 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PLG |
|---|---|
| DrugBank ID | DB00009 |
| Drug Name | Alteplase |
| Target ID | BE0000211 |
| UniProt ID | P00747 |
| Regulation Type | activator |
| PubMed IDs | 18673235; 17963464; 22248305 |
| Citations | Longstaff C, Williams S, Thelwell C: Fibrin binding and the regulation of plasminogen activators during thrombolytic therapy. Cardiovasc Hematol Agents Med Chem. 2008 Jul;6(3):212-23.@@Hilleman DE, Tsikouris JP, Seals AA, Marmur JD: Fibrinolytic agents for the management of ST-segment elevation myocardial infarction. Pharmacotherapy. 2007 Nov;27(11):1558-70.@@Acheampong P, Ford GA: Pharmacokinetics of alteplase in the treatment of ischaemic stroke. Expert Opin Drug Metab Toxicol. 2012 Feb;8(2):271-81. doi: 10.1517/17425255.2012.652615. Epub 2012 Jan 17. |
| Groups | Approved; Investigational |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | Alteplase Action Pathway |
| PharmGKB | PA164776730 |
| ChEMBL | CHEMBL1201593 |
