| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20027307 | HPV | ENSG00000198626.19 | protein_coding | RYR2 | No | No | 6262 | Q92736 |
| TVIS20047501 | HPV | ENSG00000198626.19 | protein_coding | RYR2 | No | No | 6262 | Q92736 |
| TVIS20033080 | HPV | ENSG00000198626.19 | protein_coding | RYR2 | No | No | 6262 | Q92736 |
| TVIS20066403 | HPV | ENSG00000198626.19 | protein_coding | RYR2 | No | No | 6262 | Q92736 |
| TVIS20047619 | HPV | ENSG00000198626.19 | protein_coding | RYR2 | No | No | 6262 | Q92736 |
| TVIS20037490 | HPV | ENSG00000198626.19 | protein_coding | RYR2 | No | No | 6262 | Q92736 |
| TVIS20036640 | HPV | ENSG00000198626.19 | protein_coding | RYR2 | No | No | 6262 | Q92736 |
| TVIS20048313 | HPV | ENSG00000198626.19 | protein_coding | RYR2 | No | No | 6262 | Q92736 |
| TVIS20047384 | HPV | ENSG00000198626.19 | protein_coding | RYR2 | No | No | 6262 | Q92736 |
| TVIS20048187 | HPV | ENSG00000198626.19 | protein_coding | RYR2 | No | No | 6262 | Q92736 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | RYR2 |
|---|---|
| DrugBank ID | DB01195 |
| Drug Name | Flecainide |
| Target ID | BE0005295 |
| UniProt ID | Q92736 |
| Regulation Type | inhibitor |
| PubMed IDs | 25274603 |
| Citations | Mehra D, Imtiaz MS, van Helden DF, Knollmann BC, Laver DR: Multiple modes of ryanodine receptor 2 inhibition by flecainide. Mol Pharmacol. 2014 Dec;86(6):696-706. doi: 10.1124/mol.114.094623. Epub 2014 Oct 1. |
| Groups | Approved; Withdrawn |
| Direct Classification | Benzamides |
| SMILES | FC(F)(F)COC1=CC(C(=O)NCC2CCCCN2)=C(OCC(F)(F)F)C=C1 |
| Pathways | Flecainide Action Pathway |
| PharmGKB | PA449646 |
| ChEMBL | CHEMBL652 |
