| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10036571 | HBV | ENSG00000090020.11 | protein_coding | SLC9A1 | No | No | 6548 | P19634 |
| TVIS10038427 | HBV | ENSG00000090020.11 | protein_coding | SLC9A1 | No | No | 6548 | P19634 |
| TVIS10047342 | HBV | ENSG00000090020.11 | protein_coding | SLC9A1 | No | No | 6548 | P19634 |
| TVIS10047343 | HBV | ENSG00000090020.11 | protein_coding | SLC9A1 | No | No | 6548 | P19634 |
| TVIS30005133 | HIV | ENSG00000090020.11 | protein_coding | SLC9A1 | No | No | 6548 | P19634 |
| TVIS30018231 | HIV | ENSG00000090020.11 | protein_coding | SLC9A1 | No | No | 6548 | P19634 |
| TVIS30074481 | HIV | ENSG00000090020.11 | protein_coding | SLC9A1 | No | No | 6548 | P19634 |
| TVIS30022774 | HIV | ENSG00000090020.11 | protein_coding | SLC9A1 | No | No | 6548 | P19634 |
| TVIS30022775 | HIV | ENSG00000090020.11 | protein_coding | SLC9A1 | No | No | 6548 | P19634 |
| TVIS30022776 | HIV | ENSG00000090020.11 | protein_coding | SLC9A1 | No | No | 6548 | P19634 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SLC9A1 |
|---|---|
| DrugBank ID | DB00594 |
| Drug Name | Amiloride |
| Target ID | BE0000752 |
| UniProt ID | P19634 |
| Regulation Type | inhibitor |
| PubMed IDs | 10841524; 11604219; 11688549; 12872009; 12881227 |
| Citations | Lee MG, Ahn W, Choi JY, Luo X, Seo JT, Schultheis PJ, Shull GE, Kim KH, Muallem S: Na(+)-dependent transporters mediate HCO(3)(-) salvage across the luminal membrane of the main pancreatic duct. J Clin Invest. 2000 Jun;105(11):1651-8.@@Konstantinou-Tegou A, Kaloyianni M, Bourikas D, Koliakos G: The effect of leptin on Na(+)-H(+) antiport (NHE 1) activity of obese and normal subjects erythrocytes. Mol Cell Endocrinol. 2001 Oct 25;183(1-2):11-8.@@Serrani RE, Mujica G, Gioia IA, Corchs JL: Neonatal red blood cells: amiloride-insensitive Na+-H+ transport isoform would express Na+-Li+ exchange. Acta Physiol Pharmacol Bulg. 2000;25(3-4):71-4.@@Cuthbert AW, Supuran CT, MacVinish LJ: Bicarbonate-dependent chloride secretion in Calu-3 epithelia in response to 7,8-benzoquinoline. J Physiol. 2003 Aug 15;551(Pt 1):79-92. Epub 2003 Jul 18.@@Furukawa O, Bi LC, Guth PH, Engel E, Hirokawa M, Kaunitz JD: NHE3 inhibition activates duodenal bicarbonate secretion in the rat. Am J Physiol Gastrointest Liver Physiol. 2004 Jan;286(1):G102-9. Epub 2003 Jul 24. |
| Groups | Approved |
| Direct Classification | Aminopyrazines |
| SMILES | NC(=N)NC(=O)C1=NC(Cl)=C(N)N=C1N |
| Pathways | Amiloride Action Pathway |
| PharmGKB | PA448368 |
| ChEMBL | CHEMBL945 |
