| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30007380 | HIV | ENSG00000006638.13 | protein_coding | TBXA2R | No | No | 6915 | P21731 Q05C92 Q0VAB0 |
| TVIS30081145 | HIV | ENSG00000006638.13 | protein_coding | TBXA2R | No | No | 6915 | P21731 Q05C92 Q0VAB0 |
| TVIS30047358 | HIV | ENSG00000006638.13 | protein_coding | TBXA2R | No | No | 6915 | P21731 Q05C92 Q0VAB0 |
| TVIS20008619 | HPV | ENSG00000006638.13 | protein_coding | TBXA2R | No | No | 6915 | P21731 Q05C92 Q0VAB0 |
| TVIS20023333 | HPV | ENSG00000006638.13 | protein_coding | TBXA2R | No | No | 6915 | P21731 Q05C92 Q0VAB0 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TBXA2R |
|---|---|
| DrugBank ID | DB01207 |
| Drug Name | Ridogrel |
| Target ID | BE0000759 |
| UniProt ID | P21731 |
| Regulation Type | antagonist |
| PubMed IDs | 11752352; 8831771; 8289199; 10522750; 9272380; 8697470 |
| Citations | Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Heinisch G, Holzer W, Kunz F, Langer T, Lukavsky P, Pechlaner C, Weissenberger H: On the bioisosteric potential of diazines: diazine analogues of the combined thromboxane A2 receptor antagonist and synthetase inhibitor Ridogrel. J Med Chem. 1996 Sep 27;39(20):4058-64.@@Soyka R, Heckel A, Nickl J, Eisert W, Muller TH, Weisenberger H: 6,6-Disubstituted Hex-5-enoic acid derivatives as combined thromboxane A2 receptor antagonists and synthetase inhibitors. J Med Chem. 1994 Jan 7;37(1):26-39.@@Hempelmann RG, Pradel RH, Mehdorn HM, Ziegler A: Threshold concentrations of endothelin-1: the effects on contractions induced by 5-hydroxytryptamine in isolated rat cerebral and mesenteric arteries. Pharmacol Toxicol. 1999 Sep;85(3):115-22.@@Carvalho MH, Fortes ZB, Nigro D, Oliveira MA, Scivoletto R: The role of thromboxane A2 in the altered microvascular reactivity in two-kidney, one-clip hypertension. Endothelium. 1997;5(3):167-78.@@Ragni M, Golino P, Cirillo P, Pascucci I, Scognamiglio A, Ravera A, Esposito N, Battaglia C, Guarino A, Chiariello M: [Inactivated factor VII exercises a powerful antithrombotic activity in an experimental model of recurrent arterial thrombosis]. Cardiologia. 1996 Jan;41(1):51-8. |
| Groups | Experimental |
| Direct Classification | Trifluoromethylbenzenes |
| SMILES | OC(=O)CCCCON=C(C1=CN=CC=C1)C1=CC(=CC=C1)C(F)(F)F |
| Pathways | |
| PharmGKB | PA164746413 |
| ChEMBL | CHEMBL280728 |
