| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10030004 | HBV | ENSG00000164362.21 | protein_coding | TERT | Yes | No | 7015 | O14746 |
| TVIS10030005 | HBV | ENSG00000164362.21 | protein_coding | TERT | Yes | No | 7015 | O14746 |
| TVIS10030006 | HBV | ENSG00000164362.21 | protein_coding | TERT | Yes | No | 7015 | O14746 |
| TVIS10034343 | HBV | ENSG00000164362.21 | protein_coding | TERT | Yes | No | 7015 | O14746 |
| TVIS10031756 | HBV | ENSG00000164362.21 | protein_coding | TERT | Yes | No | 7015 | O14746 |
| TVIS10033080 | HBV | ENSG00000164362.21 | protein_coding | TERT | Yes | No | 7015 | O14746 |
| TVIS10021989 | HBV | ENSG00000164362.21 | protein_coding | TERT | Yes | No | 7015 | O14746 |
| TVIS10030007 | HBV | ENSG00000164362.21 | protein_coding | TERT | Yes | No | 7015 | O14746 |
| TVIS10034961 | HBV | ENSG00000164362.21 | protein_coding | TERT | Yes | No | 7015 | O14746 |
| TVIS10034899 | HBV | ENSG00000164362.21 | protein_coding | TERT | Yes | No | 7015 | O14746 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TERT |
|---|---|
| DrugBank ID | DB00495 |
| Drug Name | Zidovudine |
| Target ID | BE0002449 |
| UniProt ID | O14746 |
| Regulation Type | inhibitor |
| PubMed IDs | 23303810 |
| Citations | Leeansyah E, Cameron PU, Solomon A, Tennakoon S, Velayudham P, Gouillou M, Spelman T, Hearps A, Fairley C, Smit de V, Pierce AB, Armishaw J, Crowe SM, Cooper DA, Koelsch KK, Liu JP, Chuah J, Lewin SR: Inhibition of telomerase activity by human immunodeficiency virus (HIV) nucleos(t)ide reverse transcriptase inhibitors: a potential factor contributing to HIV-associated accelerated aging. J Infect Dis. 2013 Apr;207(7):1157-65. doi: 10.1093/infdis/jit006. Epub 2013 Jan 9. |
| Groups | Approved |
| Direct Classification | Pyrimidine 2',3'-dideoxyribonucleosides |
| SMILES | CC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O |
| Pathways | Zidovudine Action Pathway |
| PharmGKB | PA451954 |
| ChEMBL | CHEMBL129 |
