| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44038890 | HTLV-1 | ENSG00000228716.7 | protein_coding | DHFR | No | No | 1719 | B4DM58 P00374 |
| TVIS44045050 | HTLV-1 | ENSG00000228716.7 | protein_coding | DHFR | No | No | 1719 | B4DM58 P00374 |
| TVIS44038860 | HTLV-1 | ENSG00000228716.7 | protein_coding | DHFR | No | No | 1719 | B4DM58 P00374 |
| TVIS44038846 | HTLV-1 | ENSG00000228716.7 | protein_coding | DHFR | No | No | 1719 | B4DM58 P00374 |
| TVIS44045033 | HTLV-1 | ENSG00000228716.7 | protein_coding | DHFR | No | No | 1719 | B4DM58 P00374 |
| TVIS44038859 | HTLV-1 | ENSG00000228716.7 | protein_coding | DHFR | No | No | 1719 | B4DM58 P00374 |
| TVIS44045049 | HTLV-1 | ENSG00000228716.7 | protein_coding | DHFR | No | No | 1719 | B4DM58 P00374 |
| TVIS44038858 | HTLV-1 | ENSG00000228716.7 | protein_coding | DHFR | No | No | 1719 | B4DM58 P00374 |
| TVIS44045046 | HTLV-1 | ENSG00000228716.7 | protein_coding | DHFR | No | No | 1719 | B4DM58 P00374 |
| TVIS44045059 | HTLV-1 | ENSG00000228716.7 | protein_coding | DHFR | No | No | 1719 | B4DM58 P00374 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | DHFR |
|---|---|
| DrugBank ID | DB02559 |
| Drug Name | 6-(Octahydro-1h-Indol-1-Ylmethyl)Decahydroquinazoline-2,4-Diamine |
| Target ID | BE0000330 |
| UniProt ID | P00374 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 10592235 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
| Groups | Experimental |
| Direct Classification | Quinazolines |
| SMILES | [H][C@@]12CCN(C[C@@]3([H])CC[C@]4([H])N[C@@]([H])(N)N[C@@]([H])(N)[C@]4([H])C3)[C@@]1([H])CCCC2 |
| Pathways | |
| PharmGKB | |
| ChEMBL |
