Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20055816HPVENSG00000101323.5protein_codingHAO1NoNo54363A8K058
Q9UJM8
TVIS44007934HTLV-1ENSG00000101323.5protein_codingHAO1NoNo54363A8K058
Q9UJM8
TCGA Plot Options
Drug Information
GeneHAO1
DrugBank IDDB15935
Drug NameLumasiran
Target IDBE0003766
UniProt IDQ9UJM8
Regulation Typeantisense oligonucleotide
PubMed IDs32207686
CitationsMcGregor TL, Hunt KA, Yee E, Mason D, Nioi P, Ticau S, Pelosi M, Loken PR, Finer S, Lawlor DA, Fauman EB, Huang QQ, Griffiths CJ, MacArthur DG, Trembath RC, Oglesbee D, Lieske JC, Erbe DV, Wright J, van Heel DA: Characterising a healthy adult with a rare HAO1 knockout to support a therapeutic strategy for primary hyperoxaluria. Elife. 2020 Mar 24;9. pii: 54363. doi: 10.7554/eLife.54363.
GroupsApproved; Investigational
Direct Classification
SMILES
Pathways
PharmGKB
ChEMBL