| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10012862 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS10013143 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS10013617 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS10010335 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS10008296 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS10009822 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS10010595 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS10012467 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS10013618 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
| TVIS10007908 | HBV | ENSG00000172572.7 | protein_coding | PDE3A | No | No | 5139 | Q14432 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PDE3A |
|---|---|
| DrugBank ID | DB05266 |
| Drug Name | Ibudilast |
| Target ID | BE0000436 |
| UniProt ID | Q14432 |
| Regulation Type | inhibitor |
| PubMed IDs | 21036126 |
| Citations | Yamazaki T, Anraku T, Matsuzawa S: Ibudilast, a mixed PDE3/4 inhibitor, causes a selective and nitric oxide/cGMP-independent relaxation of the intracranial vertebrobasilar artery. Eur J Pharmacol. 2011 Jan 15;650(2-3):605-11. doi: 10.1016/j.ejphar.2010.10.033. Epub 2010 Oct 29. |
| Groups | Investigational |
| Direct Classification | Pyrazolopyridines |
| SMILES | CC(C)C(=O)C1=C2C=CC=CN2N=C1C(C)C |
| Pathways | |
| PharmGKB | PA165958351 |
| ChEMBL | CHEMBL19449 |
