Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS46001147BKPyvENSG00000172572.7protein_codingPDE3ANoNo5139Q14432
TVIS46001326BKPyvENSG00000172572.7protein_codingPDE3ANoNo5139Q14432
TVIS42001156EBVENSG00000172572.7protein_codingPDE3ANoNo5139Q14432
TVIS10009443HBVENSG00000172572.7protein_codingPDE3ANoNo5139Q14432
TVIS10009444HBVENSG00000172572.7protein_codingPDE3ANoNo5139Q14432
TVIS10010334HBVENSG00000172572.7protein_codingPDE3ANoNo5139Q14432
TVIS10007991HBVENSG00000172572.7protein_codingPDE3ANoNo5139Q14432
TVIS10009525HBVENSG00000172572.7protein_codingPDE3ANoNo5139Q14432
TVIS10010594HBVENSG00000172572.7protein_codingPDE3ANoNo5139Q14432
TVIS10012210HBVENSG00000172572.7protein_codingPDE3ANoNo5139Q14432
TCGA Plot Options
Drug Information
GenePDE3A
DrugBank IDDB08811
Drug NameTofisopam
Target IDBE0000436
UniProt IDQ14432
Regulation Typeinhibitor
PubMed IDs20967473
CitationsRundfeldt C, Socala K, Wlaz P: The atypical anxiolytic drug, tofisopam, selectively blocks phosphodiesterase isoenzymes and is active in the mouse model of negative symptoms of psychosis. J Neural Transm (Vienna). 2010 Nov;117(11):1319-25. doi: 10.1007/s00702-010-0507-3. Epub 2010 Oct 22.
GroupsExperimental
Direct ClassificationBenzodiazepines
SMILESCCC1C2=CC(OC)=C(OC)C=C2C(=NN=C1C)C1=CC(OC)=C(OC)C=C1
Pathways
PharmGKBPA165958428
ChEMBLCHEMBL404216