| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30050713 | HIV | ENSG00000115353.11 | protein_coding | TACR1 | No | No | 6869 | P25103 |
| TVIS30050714 | HIV | ENSG00000115353.11 | protein_coding | TACR1 | No | No | 6869 | P25103 |
| TVIS30050715 | HIV | ENSG00000115353.11 | protein_coding | TACR1 | No | No | 6869 | P25103 |
| TVIS30050716 | HIV | ENSG00000115353.11 | protein_coding | TACR1 | No | No | 6869 | P25103 |
| TVIS20001223 | HPV | ENSG00000115353.11 | protein_coding | TACR1 | No | No | 6869 | P25103 |
| TVIS20054272 | HPV | ENSG00000115353.11 | protein_coding | TACR1 | No | No | 6869 | P25103 |
| TVIS20026602 | HPV | ENSG00000115353.11 | protein_coding | TACR1 | No | No | 6869 | P25103 |
| TVIS44004968 | HTLV-1 | ENSG00000115353.11 | protein_coding | TACR1 | No | No | 6869 | P25103 |
| TVIS44011985 | HTLV-1 | ENSG00000115353.11 | protein_coding | TACR1 | No | No | 6869 | P25103 |
| TVIS44011854 | HTLV-1 | ENSG00000115353.11 | protein_coding | TACR1 | No | No | 6869 | P25103 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TACR1 |
|---|---|
| DrugBank ID | DB09048 |
| Drug Name | Netupitant |
| Target ID | BE0000384 |
| UniProt ID | P25103 |
| Regulation Type | antagonist |
| PubMed IDs | 25687374 |
| Citations | Darmani NA, Zhong W, Chebolu S, Mercadante F: Differential and additive suppressive effects of 5-HT3 (palonosetron)- and NK1 (netupitant)-receptor antagonists on cisplatin-induced vomiting and ERK1/2, PKA and PKC activation. Pharmacol Biochem Behav. 2015 Apr;131:104-11. doi: 10.1016/j.pbb.2015.02.010. Epub 2015 Feb 14. |
| Groups | Approved; Investigational |
| Direct Classification | Pyridinylpiperazines |
| SMILES | CN(C(=O)C(C)(C)C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)C1=CN=C(C=C1C1=CC=CC=C1C)N1CCN(C)CC1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL206253 |
