Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20002629HPVENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TVIS20019180HPVENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TVIS20059732HPVENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TVIS20059954HPVENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TVIS20068180HPVENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TVIS20060061HPVENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TVIS20027263HPVENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TVIS20059257HPVENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TVIS20036596HPVENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TVIS20059580HPVENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TCGA Plot Options
Drug Information
GeneGRIA1
DrugBank IDDB08883
Drug NamePerampanel
Target IDBE0000640
UniProt IDP42261
Regulation Typeantagonist
PubMed IDs21635236
CitationsHanada T, Hashizume Y, Tokuhara N, Takenaka O, Kohmura N, Ogasawara A, Hatakeyama S, Ohgoh M, Ueno M, Nishizawa Y: Perampanel: a novel, orally active, noncompetitive AMPA-receptor antagonist that reduces seizure activity in rodent models of epilepsy. Epilepsia. 2011 Jul;52(7):1331-40. doi: 10.1111/j.1528-1167.2011.03109.x. Epub 2011 Jun 2.
GroupsApproved
Direct ClassificationBipyridines and oligopyridines
SMILESO=C1N(C=C(C=C1C1=CC=CC=C1C#N)C1=NC=CC=C1)C1=CC=CC=C1
Pathways
PharmGKB
ChEMBLCHEMBL1214124