Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS46001148BKPyvENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS46001505BKPyvENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS46000647BKPyvENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS46000379BKPyvENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS42000251EBVENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS10006386HBVENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS10018896HBVENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS10019301HBVENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS10005298HBVENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TVIS10005299HBVENSG00000113448.21protein_codingPDE4DNoNo5144A0A140VJR0
Q08499
TCGA Plot Options
Drug Information
GenePDE4D
DrugBank IDDB05266
Drug NameIbudilast
Target IDBE0001287
UniProt IDQ08499
Regulation Typeinhibitor
PubMed IDs16313925
CitationsHuang Z, Liu S, Zhang L, Salem M, Greig GM, Chan CC, Natsumeda Y, Noguchi K: Preferential inhibition of human phosphodiesterase 4 by ibudilast. Life Sci. 2006 May 1;78(23):2663-8. Epub 2005 Nov 28.
GroupsInvestigational
Direct ClassificationPyrazolopyridines
SMILESCC(C)C(=O)C1=C2C=CC=CN2N=C1C(C)C
Pathways
PharmGKBPA165958351
ChEMBLCHEMBL19449