Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS44050156HTLV-1ENSG00000184588.18protein_codingPDE4BNoNo5142Q07343
X5DNX5
X5DR82
TVIS44050157HTLV-1ENSG00000184588.18protein_codingPDE4BNoNo5142Q07343
X5DNX5
X5DR82
TCGA Plot Options
Drug Information
GenePDE4B
DrugBank IDDB03849
Drug NameCilomilast
Target IDBE0000487
UniProt IDQ07343
Regulation Typeinhibitor
PubMed IDs17155857
CitationsKroegel C, Foerster M: Phosphodiesterase-4 inhibitors as a novel approach for the treatment of respiratory disease: cilomilast. Expert Opin Investig Drugs. 2007 Jan;16(1):109-24.
GroupsInvestigational
Direct ClassificationAnisoles
SMILESCOC1=C(OC2CCCC2)C=C(C=C1)[C@]1(CC[C@@H](CC1)C(O)=O)C#N
Pathways
PharmGKB
ChEMBLCHEMBL511115