| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10011796 | HBV | ENSG00000187758.8 | protein_coding | ADH1A | No | No | 124 | P07327 |
| TVIS10011797 | HBV | ENSG00000187758.8 | protein_coding | ADH1A | No | No | 124 | P07327 |
| TVIS10019429 | HBV | ENSG00000187758.8 | protein_coding | ADH1A | No | No | 124 | P07327 |
| TVIS10059197 | HBV | ENSG00000187758.8 | protein_coding | ADH1A | No | No | 124 | P07327 |
| TVIS10059196 | HBV | ENSG00000187758.8 | protein_coding | ADH1A | No | No | 124 | P07327 |
| TVIS20065193 | HPV | ENSG00000187758.8 | protein_coding | ADH1A | No | No | 124 | P07327 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ADH1A |
|---|---|
| DrugBank ID | DB01213 |
| Drug Name | Fomepizole |
| Target ID | BE0000227 |
| UniProt ID | P07327 |
| Regulation Type | inhibitor |
| PubMed IDs | 8997246; 16790752; 2789998; 19458366; 16871118; 16946442 |
| Citations | Nagata H, Sekizuka E, Morishita T, Tatemichi M, Kurokawa T, Mizuki A, Ishii H: Adenosine A2-receptor mediates ethanol-induced arteriolar dilation in rat stomach. Am J Physiol. 1996 Dec;271(6 Pt 1):G1028-33.@@Mukherjee PK, Mohamed S, Chandra J, Kuhn D, Liu S, Antar OS, Munyon R, Mitchell AP, Andes D, Chance MR, Rouabhia M, Ghannoum MA: Alcohol dehydrogenase restricts the ability of the pathogen Candida albicans to form a biofilm on catheter surfaces through an ethanol-based mechanism. Infect Immun. 2006 Jul;74(7):3804-16.@@Nussrallah BA, Dam R, Wagner FW: Characterization of Coturnix quail liver alcohol dehydrogenase enzymes. Biochemistry. 1989 Jul 25;28(15):6245-51.@@Brent J: Fomepizole for ethylene glycol and methanol poisoning. N Engl J Med. 2009 May 21;360(21):2216-23. doi: 10.1056/NEJMct0806112.@@Calello DP, Osterhoudt KC, Henretig FM: New and novel antidotes in pediatrics. Pediatr Emerg Care. 2006 Jul;22(7):523-30.@@Betten DP, Vohra RB, Cook MD, Matteucci MJ, Clark RF: Antidote use in the critically ill poisoned patient. J Intensive Care Med. 2006 Sep-Oct;21(5):255-77. |
| Groups | Approved; Vet_approved |
| Direct Classification | Pyrazoles |
| SMILES | CC1=CNN=C1 |
| Pathways | |
| PharmGKB | PA449697 |
| ChEMBL | CHEMBL1308 |
