| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20040238 | HPV | ENSG00000113492.14 | protein_coding | AGXT2 | No | No | 64902 | Q9BYV1 |
| TVIS44045146 | HTLV-1 | ENSG00000113492.14 | protein_coding | AGXT2 | No | No | 64902 | Q9BYV1 |
| TVIS44038967 | HTLV-1 | ENSG00000113492.14 | protein_coding | AGXT2 | No | No | 64902 | Q9BYV1 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | AGXT2 |
|---|---|
| DrugBank ID | DB00119 |
| Drug Name | Pyruvic acid |
| Target ID | BE0000102 |
| UniProt ID | Q9BYV1 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 2632679 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Tamaki N, Fujimoto S, Mizota C, Kaneko M, Kikugawa M: Inhibitory effect of 6-azauracil on beta-alanine metabolism in rat. J Nutr Sci Vitaminol (Tokyo). 1989 Oct;35(5):451-61. |
| Groups | Approved; Investigational; Nutraceutical |
| Direct Classification | Alpha-keto acids and derivatives |
| SMILES | CC(=O)C(O)=O |
| Pathways | Citrullinemia Type I; 4-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency; Glycogenosis, Type IB; Argininemia; Pyruvate Kinase Deficiency; Pyruvate Carboxylase Deficiency; Amino Sugar Metabolism; The Oncogenic Action of Fumarate; 3-Phosphoglycerate Dehydrogenase Deficiency; Glycolysis; Non-Ketotic Hyperglycinemia; 2-Hydroxyglutric Aciduria (D and L Form); Glucose-Alanine Cycle; G(M2)-Gangliosidosis: Variant B, Tay-Sachs Disease; Alanine Metabolism; Hyperglycinemia, Non-Ketotic; Cystinosis, Ocular Nonnephropathic; Dimethylglycine Dehydrogenase Deficiency; Glycogenosis, Type VII. Tarui Disease; Dihydropyrimidine Dehydrogenase Deficiency (DHPD); Lactic Acidemia; Homocarnosinosis; Primary Hyperoxaluria Type I; Ornithine Transcarbamylase Deficiency (OTC Deficiency); The Oncogenic Action of L-2-Hydroxyglutarate in Hydroxygluaricaciduria; Sarcosinemia; Urea Cycle; Phosphoenolpyruvate Carboxykinase Deficiency 1 (PEPCK1); Cysteine Metabolism |
| PharmGKB | PA164778686 |
| ChEMBL | CHEMBL1162144 |
