Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10006454HBVENSG00000122787.15protein_codingAKR1D1NoNo6718P51857
TVIS10047433HBVENSG00000122787.15protein_codingAKR1D1NoNo6718P51857
TVIS30068109HIVENSG00000122787.15protein_codingAKR1D1NoNo6718P51857
TVIS20001918HPVENSG00000122787.15protein_codingAKR1D1NoNo6718P51857
TVIS20031774HPVENSG00000122787.15protein_codingAKR1D1NoNo6718P51857
TVIS20041588HPVENSG00000122787.15protein_codingAKR1D1NoNo6718P51857
TVIS44032372HTLV-1ENSG00000122787.15protein_codingAKR1D1NoNo6718P51857
TVIS44000012HTLV-1ENSG00000122787.15protein_codingAKR1D1NoNo6718P51857
TCGA Plot Options
Drug Information
GeneAKR1D1
DrugBank IDDB01216
Drug NameFinasteride
Target IDBE0003610
UniProt IDP51857
Regulation Typeinhibitor
PubMed IDs19515843
CitationsDrury JE, Di Costanzo L, Penning TM, Christianson DW: Inhibition of human steroid 5beta-reductase (AKR1D1) by finasteride and structure of the enzyme-inhibitor complex. J Biol Chem. 2009 Jul 24;284(30):19786-90. doi: 10.1074/jbc.C109.016931. Epub 2009 Jun 10.
GroupsApproved
Direct ClassificationAndrogens and derivatives
SMILES[H][C@@]12CC[C@H](C(=O)NC(C)(C)C)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])NC(=O)C=C[C@]12C
Pathways
PharmGKBPA449627
ChEMBLCHEMBL710