Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20066966HPVENSG00000165092.13protein_codingALDH1A1NoNo216P00352
TVIS20020756HPVENSG00000165092.13protein_codingALDH1A1NoNo216P00352
TVIS20020573HPVENSG00000165092.13protein_codingALDH1A1NoNo216P00352
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Drug Information
GeneALDH1A1
DrugBank IDDB00162
Drug NameVitamin A
Target IDBE0000554
UniProt IDP00352
Regulation Typesubstrate
PubMed IDs16538685; 17329364; 16829625; 17486539; 16763553
CitationsAsson-Batres MA, Smith WB: Localization of retinaldehyde dehydrogenases and retinoid binding proteins to sustentacular cells, glia, Bowman's gland cells, and stroma: potential sites of retinoic acid synthesis in the postnatal rat olfactory organ. J Comp Neurol. 2006 May 10;496(2):149-71.@@Chambers D, Wilson L, Maden M, Lumsden A: RALDH-independent generation of retinoic acid during vertebrate embryogenesis by CYP1B1. Development. 2007 Apr;134(7):1369-83. Epub 2007 Feb 28.@@Gyamfi MA, Kocsis MG, He L, Dai G, Mendy AJ, Wan YJ: The role of retinoid X receptor alpha in regulating alcohol metabolism. J Pharmacol Exp Ther. 2006 Oct;319(1):360-8. Epub 2006 Jul 7.@@Maden M, Blentic A, Reijntjes S, Seguin S, Gale E, Graham A: Retinoic acid is required for specification of the ventral eye field and for Rathke's pouch in the avian embryo. Int J Dev Biol. 2007;51(3):191-200.@@Huq MD, Tsai NP, Gupta P, Wei LN: Regulation of retinal dehydrogenases and retinoic acid synthesis by cholesterol metabolites. EMBO J. 2006 Jul 12;25(13):3203-13. Epub 2006 Jun 8.
GroupsApproved; Nutraceutical; Vet_approved
Direct ClassificationRetinoids
SMILESCC(=C/CO)C=CC=C(/C)C=CC1=C(C)CCCC1(C)C
PathwaysRetinol Metabolism; Vitamin A Deficiency
PharmGKBPA451884
ChEMBLCHEMBL986