| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44004692 | HTLV-1 | ENSG00000128918.15 | protein_coding | ALDH1A2 | No | No | 8854 | O94788 |
| TVIS44000626 | HTLV-1 | ENSG00000128918.15 | protein_coding | ALDH1A2 | No | No | 8854 | O94788 |
| TVIS44041804 | HTLV-1 | ENSG00000128918.15 | protein_coding | ALDH1A2 | No | No | 8854 | O94788 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ALDH1A2 |
|---|---|
| DrugBank ID | DB00162 |
| Drug Name | Vitamin A |
| Target ID | BE0000513 |
| UniProt ID | O94788 |
| Regulation Type | substrate |
| PubMed IDs | 17098734; 17184764; 16538685; 16982809; 17270546 |
| Citations | Isken A, Holzschuh J, Lampert JM, Fischer L, Oberhauser V, Palczewski K, von Lintig J: Sequestration of retinyl esters is essential for retinoid signaling in the zebrafish embryo. J Biol Chem. 2007 Jan 12;282(2):1144-51. Epub 2006 Nov 10.@@Halilagic A, Ribes V, Ghyselinck NB, Zile MH, Dolle P, Studer M: Retinoids control anterior and dorsal properties in the developing forebrain. Dev Biol. 2007 Mar 1;303(1):362-75. Epub 2006 Nov 17.@@Asson-Batres MA, Smith WB: Localization of retinaldehyde dehydrogenases and retinoid binding proteins to sustentacular cells, glia, Bowman's gland cells, and stroma: potential sites of retinoic acid synthesis in the postnatal rat olfactory organ. J Comp Neurol. 2006 May 10;496(2):149-71.@@Szatmari I, Pap A, Ruhl R, Ma JX, Illarionov PA, Besra GS, Rajnavolgyi E, Dezso B, Nagy L: PPARgamma controls CD1d expression by turning on retinoic acid synthesis in developing human dendritic cells. J Exp Med. 2006 Oct 2;203(10):2351-62. Epub 2006 Sep 18.@@Nakazawa N, Montedonico S, Takayasu H, Paradisi F, Puri P: Disturbance of retinol transportation causes nitrofen-induced hypoplastic lung. J Pediatr Surg. 2007 Feb;42(2):345-9. |
| Groups | Approved; Nutraceutical; Vet_approved |
| Direct Classification | Retinoids |
| SMILES | CC(=C/CO)C=CC=C(/C)C=CC1=C(C)CCCC1(C)C |
| Pathways | Retinol Metabolism; Vitamin A Deficiency |
| PharmGKB | PA451884 |
| ChEMBL | CHEMBL986 |
