| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10046984 | HBV | ENSG00000171094.18 | protein_coding | ALK | Yes | No | 238 | B6D4Y2 Q9UM73 |
| TVIS10046985 | HBV | ENSG00000171094.18 | protein_coding | ALK | Yes | No | 238 | B6D4Y2 Q9UM73 |
| TVIS10045458 | HBV | ENSG00000171094.18 | protein_coding | ALK | Yes | No | 238 | B6D4Y2 Q9UM73 |
| TVIS30085699 | HIV | ENSG00000171094.18 | protein_coding | ALK | Yes | No | 238 | B6D4Y2 Q9UM73 |
| TVIS30078541 | HIV | ENSG00000171094.18 | protein_coding | ALK | Yes | No | 238 | B6D4Y2 Q9UM73 |
| TVIS30079601 | HIV | ENSG00000171094.18 | protein_coding | ALK | Yes | No | 238 | B6D4Y2 Q9UM73 |
| TVIS30082050 | HIV | ENSG00000171094.18 | protein_coding | ALK | Yes | No | 238 | B6D4Y2 Q9UM73 |
| TVIS30078760 | HIV | ENSG00000171094.18 | protein_coding | ALK | Yes | No | 238 | B6D4Y2 Q9UM73 |
| TVIS30050023 | HIV | ENSG00000171094.18 | protein_coding | ALK | Yes | No | 238 | B6D4Y2 Q9UM73 |
| TVIS30050024 | HIV | ENSG00000171094.18 | protein_coding | ALK | Yes | No | 238 | B6D4Y2 Q9UM73 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ALK |
|---|---|
| DrugBank ID | DB08865 |
| Drug Name | Crizotinib |
| Target ID | BE0000359 |
| UniProt ID | Q9UM73 |
| Regulation Type | inhibitor |
| PubMed IDs | 22594847 |
| Citations | Forde PM, Rudin CM: Crizotinib in the treatment of non-small-cell lung cancer. Expert Opin Pharmacother. 2012 Jun;13(8):1195-201. doi: 10.1517/14656566.2012.688029. |
| Groups | Approved; Investigational |
| Direct Classification | Pyrazolylpyridines |
| SMILES | C[C@@H](OC1=CC(=CN=C1N)C1=CN(N=C1)C1CCNCC1)C1=C(Cl)C=CC(F)=C1Cl |
| Pathways | |
| PharmGKB | PA165946122 |
| ChEMBL | CHEMBL601719 |
