Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20060431HPVENSG00000123505.20protein_codingAMD1NoNo262B4DZ60
P17707
Q5VXN5
TCGA Plot Options
Drug Information
GeneAMD1
DrugBank IDDB01917
Drug NamePutrescine
Target IDBE0000101
UniProt IDP17707
Regulation Type
PubMed IDs17139284; 17016423
CitationsOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.
GroupsExperimental
Direct ClassificationMonoalkylamines
SMILESNCCCCN
PathwaysMethionine Metabolism; S-Adenosylhomocysteine (SAH) Hydrolase Deficiency; Methionine Adenosyltransferase Deficiency; Cystathionine beta-Synthase Deficiency; Glycine N-Methyltransferase Deficiency; Spermidine and Spermine Biosynthesis; Methylenetetrahydrofolate Reductase Deficiency (MTHFRD); Homocystinuria-Megaloblastic Anemia Due to Defect in Cobalamin Metabolism, cblG Complementation Type; Hypermethioninemia
PharmGKB
ChEMBLCHEMBL46257