Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10000171HBVENSG00000091879.14protein_codingANGPT2NoNo285O15123
TVIS30009474HIVENSG00000091879.14protein_codingANGPT2NoNo285O15123
TVIS30084026HIVENSG00000091879.14protein_codingANGPT2NoNo285O15123
TVIS20000688HPVENSG00000091879.14protein_codingANGPT2NoNo285O15123
TCGA Plot Options
Drug Information
GeneANGPT2
DrugBank IDDB15303
Drug NameFaricimab
Target IDBE0010028
UniProt IDO15123
Regulation Typeantagonist
PubMed IDs27742718
CitationsRegula JT, Lundh von Leithner P, Foxton R, Barathi VA, Cheung CM, Bo Tun SB, Wey YS, Iwata D, Dostalek M, Moelleken J, Stubenrauch KG, Nogoceke E, Widmer G, Strassburger P, Koss MJ, Klein C, Shima DT, Hartmann G: Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases. EMBO Mol Med. 2016 Nov 2;8(11):1265-1288. doi: 10.15252/emmm.201505889. Print 2016 Nov.
GroupsApproved; Investigational
Direct ClassificationPeptides
SMILES
Pathways
PharmGKB
ChEMBL