Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30088508HIVENSG00000130643.9protein_codingCALYNoNo50632Q9NYX4
TCGA Plot Options
Drug Information
GeneCALY
DrugBank IDDB00831
Drug NameTrifluoperazine
Target IDBE0000666
UniProt IDQ9NYX4
Regulation Typeantagonist
PubMed IDs11752352; 945467; 17407813
CitationsChen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Seeman P, Lee T, Chau-Wong M, Wong K: Antipsychotic drug doses and neuroleptic/dopamine receptors. Nature. 1976 Jun 24;261(5562):717-9.@@Madrid PB, Polgar WE, Toll L, Tanga MJ: Synthesis and antitubercular activity of phenothiazines with reduced binding to dopamine and serotonin receptors. Bioorg Med Chem Lett. 2007 Jun 1;17(11):3014-7. Epub 2007 Mar 24.
GroupsApproved; Investigational
Direct ClassificationPhenothiazines
SMILESCN1CCN(CCCN2C3=CC=CC=C3SC3=C2C=C(C=C3)C(F)(F)F)CC1
Pathways
PharmGKBPA451771
ChEMBLCHEMBL422