| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30029338 | HIV | ENSG00000026508.21 | protein_coding | CD44 | No | No | 960 | P16070 |
| TVIS30017833 | HIV | ENSG00000026508.21 | protein_coding | CD44 | No | No | 960 | P16070 |
| TVIS30017952 | HIV | ENSG00000026508.21 | protein_coding | CD44 | No | No | 960 | P16070 |
| TVIS20026789 | HPV | ENSG00000026508.21 | protein_coding | CD44 | No | No | 960 | P16070 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | CD44 |
|---|---|
| DrugBank ID | DB08818 |
| Drug Name | Hyaluronic acid |
| Target ID | BE0001113 |
| UniProt ID | P16070 |
| Regulation Type | binder |
| PubMed IDs | 15725890; 7542594; 10871609; 31294035 |
| Citations | Higa K, Shimmura S, Shimazaki J, Tsubota K: Hyaluronic acid-CD44 interaction mediates the adhesion of lymphocytes by amniotic membrane stroma. Cornea. 2005 Mar;24(2):206-12. doi: 10.1097/01.ico.0000133999.45262.83.@@Uff CR, Neame SJ, Isacke CM: Hyaluronan binding by CD44 is regulated by a phosphorylation-independent mechanism. Eur J Immunol. 1995 Jul;25(7):1883-7. doi: 10.1002/eji.1830250714.@@Lesley J, Hascall VC, Tammi M, Hyman R: Hyaluronan binding by cell surface CD44. J Biol Chem. 2000 Sep 1;275(35):26967-75. doi: 10.1074/jbc.M002527200.@@Gupta RC, Lall R, Srivastava A, Sinha A: Hyaluronic Acid: Molecular Mechanisms and Therapeutic Trajectory. Front Vet Sci. 2019 Jun 25;6:192. doi: 10.3389/fvets.2019.00192. eCollection 2019. |
| Groups | Approved; Vet_approved |
| Direct Classification | Acylaminosugars |
| SMILES | CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)C1O[C@@H]1O[C@@H]([C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)C(O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(O)=O)[C@H]2NC(C)=O)[C@H](O)[C@H]1O)C(O)=O |
| Pathways | |
| PharmGKB | PA165958431 |
| ChEMBL |
