| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10000114 | HBV | ENSG00000114013.16 | protein_coding | CD86 | No | No | 942 | A0A0X9R4E0 P42081 |
| TVIS20034964 | HPV | ENSG00000114013.16 | protein_coding | CD86 | No | No | 942 | A0A0X9R4E0 P42081 |
| TVIS20057570 | HPV | ENSG00000114013.16 | protein_coding | CD86 | No | No | 942 | A0A0X9R4E0 P42081 |
| TVIS20021046 | HPV | ENSG00000114013.16 | protein_coding | CD86 | No | No | 942 | A0A0X9R4E0 P42081 |
| TVIS20037666 | HPV | ENSG00000114013.16 | protein_coding | CD86 | No | No | 942 | A0A0X9R4E0 P42081 |
| TVIS44005921 | HTLV-1 | ENSG00000114013.16 | protein_coding | CD86 | No | No | 942 | A0A0X9R4E0 P42081 |
Target Gene Table
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TCGA Plot Options
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Drug Information
▼
| Gene | CD86 |
|---|---|
| DrugBank ID | DB01281 |
| Drug Name | Abatacept |
| Target ID | BE0000846 |
| UniProt ID | P42081 |
| Regulation Type | antagonist |
| PubMed IDs | 16971318; 17020493; 16357751; 16932686; 20080922; 17212998; 16573350; 18041889; 11752352 |
| Citations | Scheinfeld N: Abatacept: A review of a new biologic agent for refractory rheumatoid arthritis for dermatologists. J Dermatolog Treat. 2006;17(4):229-34.@@Vincenti F, Luggen M: T cell costimulation: a rational target in the therapeutic armamentarium for autoimmune diseases and transplantation. Annu Rev Med. 2007;58:347-58.@@Kremer JM: Selective costimulation modulators: a novel approach for the treatment of rheumatoid arthritis. J Clin Rheumatol. 2005 Jun;11(3 Suppl):S55-62.@@Weyand CM, Goronzy JJ: T-cell-targeted therapies in rheumatoid arthritis. Nat Clin Pract Rheumatol. 2006 Apr;2(4):201-10.@@Maxwell LJ, Singh JA: Abatacept for rheumatoid arthritis: a Cochrane systematic review. J Rheumatol. 2010 Feb;37(2):234-45. doi: 10.3899/jrheum.091066. Epub 2010 Jan 15.@@Nogid A, Pham DQ: Role of abatacept in the management of rheumatoid arthritis. Clin Ther. 2006 Nov;28(11):1764-78.@@Hervey PS, Keam SJ: Abatacept. BioDrugs. 2006;20(1):53-61; discussion 62.@@Reynolds J, Shojania K, Marra CA: Abatacept: a novel treatment for moderate-to-severe rheumatoid arthritis. Pharmacotherapy. 2007 Dec;27(12):1693-701.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | PA164747080 |
| ChEMBL | CHEMBL1201823 |
