VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
---|---|---|---|---|---|---|---|---|
TVIS30065498 | HIV | ENSG00000118432.13 | protein_coding | CNR1 | No | No | 1268 | P21554 S5TLS4 V5KA96 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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Gene | CNR1 |
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DrugBank ID | DB00486 |
Drug Name | Nabilone |
Target ID | BE0000061 |
UniProt ID | P21554 |
Regulation Type | partial agonist |
PubMed IDs | 17139494; 11698062; 8981483; 10575283; 8864542; 11752352 |
Citations | Davis M, Maida V, Daeninck P, Pergolizzi J: The emerging role of cannabinoid neuromodulators in symptom management. Support Care Cancer. 2007 Jan;15(1):63-71. Epub 2006 Dec 1.@@Darmani NA: The cannabinoid CB1 receptor antagonist SR 141716A reverses the antiemetic and motor depressant actions of WIN 55, 212-2. Eur J Pharmacol. 2001 Oct 26;430(1):49-58.@@Hirst RA, Almond SL, Lambert DG: Characterisation of the rat cerebella CB1 receptor using SR141716A, a central cannabinoid receptor antagonist. Neurosci Lett. 1996 Dec 13;220(2):101-4.@@Pertwee RG: Cannabis and cannabinoids: pharmacology and rationale for clinical use. Forsch Komplementarmed. 1999 Oct;6 Suppl 3:12-5.@@Pertwee RG, Fernando SR: Evidence for the presence of cannabinoid CB1 receptors in mouse urinary bladder. Br J Pharmacol. 1996 Aug;118(8):2053-8.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
Groups | Approved; Investigational |
Direct Classification | Naphthopyranones |
SMILES | [H][C@@]12CC(=O)CC[C@@]1([H])C(C)(C)OC1=CC(=CC(O)=C21)C(C)(C)CCCCCC |
Pathways | |
PharmGKB | PA164746998 |
ChEMBL | CHEMBL947 |