| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30052257 | HIV | ENSG00000118260.15 | protein_coding | CREB1 | Yes | No | 1385 | P16220 Q53X93 Q5U0J5 |
| TVIS20032878 | HPV | ENSG00000118260.15 | protein_coding | CREB1 | Yes | No | 1385 | P16220 Q53X93 Q5U0J5 |
| TVIS20039382 | HPV | ENSG00000118260.15 | protein_coding | CREB1 | Yes | No | 1385 | P16220 Q53X93 Q5U0J5 |
| TVIS20046358 | HPV | ENSG00000118260.15 | protein_coding | CREB1 | Yes | No | 1385 | P16220 Q53X93 Q5U0J5 |
| TVIS20055557 | HPV | ENSG00000118260.15 | protein_coding | CREB1 | Yes | No | 1385 | P16220 Q53X93 Q5U0J5 |
| TVIS20014243 | HPV | ENSG00000118260.15 | protein_coding | CREB1 | Yes | No | 1385 | P16220 Q53X93 Q5U0J5 |
| TVIS50000018 | MLV | ENSG00000118260.15 | protein_coding | CREB1 | Yes | No | 1385 | P16220 Q53X93 Q5U0J5 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CREB1 |
|---|---|
| DrugBank ID | DB01183 |
| Drug Name | Naloxone |
| Target ID | BE0000958 |
| UniProt ID | P16220 |
| Regulation Type | other/unknown |
| PubMed IDs | 12956944; 12969258; 14653953; 15953421; 16417577 |
| Citations | Li J, Li YH, Yuan XR: Changes of phosphorylation of cAMP response element binding protein in rat nucleus accumbens after chronic ethanol intake: naloxone reversal. Acta Pharmacol Sin. 2003 Sep;24(9):930-6.@@Chartoff EH, Papadopoulou M, Konradi C, Carlezon WA Jr: Dopamine-dependent increases in phosphorylation of cAMP response element binding protein (CREB) during precipitated morphine withdrawal in primary cultures of rat striatum. J Neurochem. 2003 Oct;87(1):107-18.@@Gao C, Chen LW, Tao YM, Chen J, Xu XJ, Chi ZQ: Effects of ohmefentanyl stereoisomers on phosphorylation of cAMP- response element binding protein in cultured rat hippocampal neurons. Acta Pharmacol Sin. 2003 Dec;24(12):1253-8.@@Walters CL, Cleck JN, Kuo YC, Blendy JA: Mu-opioid receptor and CREB activation are required for nicotine reward. Neuron. 2005 Jun 16;46(6):933-43.@@Hawes JJ, Narasimhaiah R, Picciotto MR: Galanin attenuates cyclic AMP regulatory element-binding protein (CREB) phosphorylation induced by chronic morphine and naloxone challenge in Cath.a cells and primary striatal cultures. J Neurochem. 2006 Feb;96(4):1160-8. Epub 2006 Jan 17. |
| Groups | Approved; Vet_approved |
| Direct Classification | Phenanthrenes and derivatives |
| SMILES | OC1=CC=C2C[C@H]3N(CC=C)CC[C@@]45[C@@H](OC1=C24)C(=O)CC[C@@]35O |
| Pathways | Naloxone Action Pathway |
| PharmGKB | PA450586 |
| ChEMBL | CHEMBL80 |
