Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20049248HPVENSG00000165841.11protein_codingCYP2C19NoNo1557P33261
TVIS44031178HTLV-1ENSG00000165841.11protein_codingCYP2C19NoNo1557P33261
TCGA Plot Options
Drug Information
GeneCYP2C19
DrugBank IDDB12319
Drug NameBenzbromarone
Target IDBE0003536
UniProt IDP33261
Regulation Typeinhibitor
PubMed IDs15615526
CitationsLocuson CW 2nd, Suzuki H, Rettie AE, Jones JP: Charge and substituent effects on affinity and metabolism of benzbromarone-based CYP2C19 inhibitors. J Med Chem. 2004 Dec 30;47(27):6768-76.
GroupsInvestigational; Withdrawn
Direct ClassificationAryl-phenylketones
SMILESCCC1=C(C(=O)C2=CC(Br)=C(O)C(Br)=C2)C2=CC=CC=C2O1
Pathways
PharmGKB
ChEMBLCHEMBL388590