| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44036931 | HTLV-1 | ENSG00000153904.21 | protein_coding | DDAH1 | No | No | 23576 | B1AKK2 B4DYP1 O94760 |
| TVIS44037076 | HTLV-1 | ENSG00000153904.21 | protein_coding | DDAH1 | No | No | 23576 | B1AKK2 B4DYP1 O94760 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | DDAH1 |
|---|---|
| DrugBank ID | DB00213 |
| Drug Name | Pantoprazole |
| Target ID | BE0000766 |
| UniProt ID | O94760 |
| Regulation Type | inhibitor |
| PubMed IDs | 23825361; 28588208 |
| Citations | Ghebremariam YT, LePendu P, Lee JC, Erlanson DA, Slaviero A, Shah NH, Leiper J, Cooke JP: Unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine. Circulation. 2013 Aug 20;128(8):845-53. doi: 10.1161/CIRCULATIONAHA.113.003602. Epub 2013 Jul 3.@@Tommasi S, Elliot DJ, Hulin JA, Lewis BC, McEvoy M, Mangoni AA: Human dimethylarginine dimethylaminohydrolase 1 inhibition by proton pump inhibitors and the cardiovascular risk marker asymmetric dimethylarginine: in vitro and in vivo significance. Sci Rep. 2017 Jun 6;7(1):2871. doi: 10.1038/s41598-017-03069-1. |
| Groups | Approved |
| Direct Classification | Sulfinylbenzimidazoles |
| SMILES | COC1=C(OC)C(CS(=O)C2=NC3=C(N2)C=C(OC(F)F)C=C3)=NC=C1 |
| Pathways | Pantoprazole Metabolism Pathway; Pantoprazole Action Pathway |
| PharmGKB | PA450774 |
| ChEMBL | CHEMBL1502 |
