Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS42001170EBVENSG00000108515.18protein_codingENO3NoNo2027P13929
TVIS30042704HIVENSG00000108515.18protein_codingENO3NoNo2027P13929
TVIS20031952HPVENSG00000108515.18protein_codingENO3NoNo2027P13929
TCGA Plot Options
Drug Information
GeneENO3
DrugBank IDDB01819
Drug NamePhosphoenolpyruvate
Target IDBE0004460
UniProt IDP13929
Regulation Type
PubMed IDs17139284; 17016423; 10592235
CitationsOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
GroupsExperimental
Direct ClassificationPhosphate esters
SMILESOC(=O)C(=C)OP(O)(O)=O
PathwaysLeigh Syndrome; Glycogenosis, Type IB; Pyruvate Kinase Deficiency; Pyruvate Dehydrogenase Complex Deficiency; Tay-Sachs Disease; Amino Sugar Metabolism; Warburg Effect; Fructose-1,6-diphosphatase Deficiency; Glycogenosis, Type IC; Glycolysis; Glycogenosis, Type IA. Von Gierke Disease; Salla Disease/Infantile Sialic Acid Storage Disease; Gluconeogenesis; Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency); G(M2)-Gangliosidosis: Variant B, Tay-Sachs Disease; Pyruvate Metabolism; Primary Hyperoxaluria II, PH2; Glycogenosis, Type VII. Tarui Disease; Sialuria or French Type Sialuria; Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease; Fanconi-Bickel Syndrome; Triosephosphate Isomerase; Phosphoenolpyruvate Carboxykinase Deficiency 1 (PEPCK1)
PharmGKB
ChEMBLCHEMBL1235228