| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10017592 | HBV | ENSG00000116016.14 | protein_coding | EPAS1 | No | No | 2034 | Q99814 |
| TVIS10017800 | HBV | ENSG00000116016.14 | protein_coding | EPAS1 | No | No | 2034 | Q99814 |
| TVIS10017801 | HBV | ENSG00000116016.14 | protein_coding | EPAS1 | No | No | 2034 | Q99814 |
| TVIS10017802 | HBV | ENSG00000116016.14 | protein_coding | EPAS1 | No | No | 2034 | Q99814 |
| TVIS10017803 | HBV | ENSG00000116016.14 | protein_coding | EPAS1 | No | No | 2034 | Q99814 |
| TVIS30083715 | HIV | ENSG00000116016.14 | protein_coding | EPAS1 | No | No | 2034 | Q99814 |
| TVIS44000423 | HTLV-1 | ENSG00000116016.14 | protein_coding | EPAS1 | No | No | 2034 | Q99814 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | EPAS1 |
|---|---|
| DrugBank ID | DB15463 |
| Drug Name | Belzutifan |
| Target ID | BE0009679 |
| UniProt ID | Q99814 |
| Regulation Type | inhibitor |
| PubMed IDs | |
| Citations | Tai W. Wong, Rajeev Shrimali, Cristina Contreras, Tzuling Cheng, Robert M. Czerwinski, Daryl D. Dixon, Xinlin Du, Craig Fett, Jessica Goree, Jonas A. Grina, Guangzhou Han, Heli Huang, Jim Rizzi, Stephen T. Schlachter, Bin Wang, Keshi Wang, Paul M. Wehn, Shanhai Xie, Rui Xu, Hanbiao Yang, John A. Josey and Eli M. Wallace: Abstract B140: PT2977, a novel HIF-2a antagonist, has potent antitumor activity and remodels the immunosuppressive tumor microenvironment in clear cell renal cell cancer AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics. |
| Groups | Approved; Investigational |
| Direct Classification | |
| SMILES | CS(=O)(=O)C1=CC=C(OC2=CC(=CC(F)=C2)C#N)C2=C1[C@H](O)[C@H](F)[C@@H]2F |
| Pathways | |
| PharmGKB | PA166268761 |
| ChEMBL | CHEMBL4585668 |
