| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS46000920 | BKPyv | ENSG00000088832.18 | protein_coding | FKBP1A | No | No | 2280 | A0A087WTS4 P62942 Q0VDC6 |
| TVIS30003249 | HIV | ENSG00000088832.18 | protein_coding | FKBP1A | No | No | 2280 | A0A087WTS4 P62942 Q0VDC6 |
| TVIS30052808 | HIV | ENSG00000088832.18 | protein_coding | FKBP1A | No | No | 2280 | A0A087WTS4 P62942 Q0VDC6 |
| TVIS30052809 | HIV | ENSG00000088832.18 | protein_coding | FKBP1A | No | No | 2280 | A0A087WTS4 P62942 Q0VDC6 |
| TVIS30052810 | HIV | ENSG00000088832.18 | protein_coding | FKBP1A | No | No | 2280 | A0A087WTS4 P62942 Q0VDC6 |
| TVIS30052811 | HIV | ENSG00000088832.18 | protein_coding | FKBP1A | No | No | 2280 | A0A087WTS4 P62942 Q0VDC6 |
| TVIS44011712 | HTLV-1 | ENSG00000088832.18 | protein_coding | FKBP1A | No | No | 2280 | A0A087WTS4 P62942 Q0VDC6 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | FKBP1A |
|---|---|
| DrugBank ID | DB00864 |
| Drug Name | Tacrolimus |
| Target ID | BE0000695 |
| UniProt ID | P62942 |
| Regulation Type | inhibitor |
| PubMed IDs | 16289353; 17524933 |
| Citations | Labrande C, Velly L, Canolle B, Guillet B, Masmejean F, Nieoullon A, Pisano P: Neuroprotective effects of tacrolimus (FK506) in a model of ischemic cortical cell cultures: role of glutamate uptake and FK506 binding protein 12 kDa. Neuroscience. 2006;137(1):231-9. Epub 2005 Nov 10.@@Masri M, Rizk S, Barbari A, Stephan A, Kamel G, Rost M: An assay for the determination of sirolimus levels in the lymphocyte of transplant patients. Transplant Proc. 2007 May;39(4):1204-6. |
| Groups | Approved; Investigational |
| Direct Classification | Macrolide lactams |
| SMILES | CO[C@@H]1C[C@@H](CC[C@H]1O)C=C(/C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@H](C[C@@H](C)CC(C)=C[C@@H](CC=C)C(=O)C[C@H](O)[C@H]1C)OC |
| Pathways | |
| PharmGKB | PA451578 |
| ChEMBL | CHEMBL269732 |
