| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30014538 | HIV | ENSG00000162613.18 | protein_coding | FUBP1 | No | Yes | 8880 | Q96AE4 |
| TVIS30024154 | HIV | ENSG00000162613.18 | protein_coding | FUBP1 | No | Yes | 8880 | Q96AE4 |
| TVIS30024155 | HIV | ENSG00000162613.18 | protein_coding | FUBP1 | No | Yes | 8880 | Q96AE4 |
| TVIS30024156 | HIV | ENSG00000162613.18 | protein_coding | FUBP1 | No | Yes | 8880 | Q96AE4 |
| TVIS30024157 | HIV | ENSG00000162613.18 | protein_coding | FUBP1 | No | Yes | 8880 | Q96AE4 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | FUBP1 |
|---|---|
| DrugBank ID | DB12893 |
| Drug Name | Sacituzumab govitecan |
| Target ID | BE0003422 |
| UniProt ID | Q96AE4 |
| Regulation Type | inhibitor |
| PubMed IDs | 29031818 |
| Citations | Khageh Hosseini S, Kolterer S, Steiner M, von Manstein V, Gerlach K, Trojan J, Waidmann O, Zeuzem S, Schulze JO, Hahn S, Steinhilber D, Gatterdam V, Tampe R, Biondi RM, Proschak E, Zornig M: Camptothecin and its analog SN-38, the active metabolite of irinotecan, inhibit binding of the transcriptional regulator and oncoprotein FUBP1 to its DNA target sequence FUSE. Biochem Pharmacol. 2017 Dec 15;146:53-62. doi: 10.1016/j.bcp.2017.10.003. Epub 2017 Oct 13. |
| Groups | Approved; Investigational |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | |
| ChEMBL |
