| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10012216 | HBV | ENSG00000167588.13 | protein_coding | GPD1 | No | No | 2819 | A0A024R138 P21695 |
| TVIS10012217 | HBV | ENSG00000167588.13 | protein_coding | GPD1 | No | No | 2819 | A0A024R138 P21695 |
| TVIS10011488 | HBV | ENSG00000167588.13 | protein_coding | GPD1 | No | No | 2819 | A0A024R138 P21695 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GPD1 |
|---|---|
| DrugBank ID | DB00331 |
| Drug Name | Metformin |
| Target ID | BE0000208 |
| UniProt ID | P21695 |
| Regulation Type | inhibitor |
| PubMed IDs | 24847880; 25100057 |
| Citations | Madiraju AK, Erion DM, Rahimi Y, Zhang XM, Braddock DT, Albright RA, Prigaro BJ, Wood JL, Bhanot S, MacDonald MJ, Jurczak MJ, Camporez JP, Lee HY, Cline GW, Samuel VT, Kibbey RG, Shulman GI: Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase. Nature. 2014 Jun 26;510(7506):542-6. doi: 10.1038/nature13270. Epub 2014 May 21.@@Baur JA, Birnbaum MJ: Control of gluconeogenesis by metformin: does redox trump energy charge? Cell Metab. 2014 Aug 5;20(2):197-9. doi: 10.1016/j.cmet.2014.07.013. |
| Groups | Approved |
| Direct Classification | Biguanides |
| SMILES | CN(C)C(=N)NC(N)=N |
| Pathways | |
| PharmGKB | PA450395 |
| ChEMBL | CHEMBL1431 |
