| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30002808 | HIV | ENSG00000177885.15 | protein_coding | GRB2 | No | No | 2885 | B0LPF3 P62993 |
| TVIS30007215 | HIV | ENSG00000177885.15 | protein_coding | GRB2 | No | No | 2885 | B0LPF3 P62993 |
| TVIS30002809 | HIV | ENSG00000177885.15 | protein_coding | GRB2 | No | No | 2885 | B0LPF3 P62993 |
| TVIS30002810 | HIV | ENSG00000177885.15 | protein_coding | GRB2 | No | No | 2885 | B0LPF3 P62993 |
| TVIS30015539 | HIV | ENSG00000177885.15 | protein_coding | GRB2 | No | No | 2885 | B0LPF3 P62993 |
| TVIS30007216 | HIV | ENSG00000177885.15 | protein_coding | GRB2 | No | No | 2885 | B0LPF3 P62993 |
| TVIS30014379 | HIV | ENSG00000177885.15 | protein_coding | GRB2 | No | No | 2885 | B0LPF3 P62993 |
| TVIS30015540 | HIV | ENSG00000177885.15 | protein_coding | GRB2 | No | No | 2885 | B0LPF3 P62993 |
| TVIS30016936 | HIV | ENSG00000177885.15 | protein_coding | GRB2 | No | No | 2885 | B0LPF3 P62993 |
| TVIS30075540 | HIV | ENSG00000177885.15 | protein_coding | GRB2 | No | No | 2885 | B0LPF3 P62993 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GRB2 |
|---|---|
| DrugBank ID | DB03276 |
| Drug Name | 4-[(10s,14s,18s)-18-(2-Amino-2-Oxoethyl)-14-(1-Naphthylmethyl)-8,17,20-Trioxo-7,16,19-Triazaspiro[5.14]Icos-11-En-10-Yl]Benzylphosphonic Acid |
| Target ID | BE0000917 |
| UniProt ID | P62993 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 10592235 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
| Groups | Experimental |
| Direct Classification | Cyclic peptides |
| SMILES | NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)C[C@H](C=CC[C@H](CNC1=O)CC1=CC=CC2=CC=CC=C12)C1=CC=C(C=C1)CP(O)(O)=O |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL291678 |
