| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30080939 | HIV | ENSG00000068024.18 | protein_coding | HDAC4 | Yes | Yes | 9759 | P56524 |
| TVIS30082582 | HIV | ENSG00000068024.18 | protein_coding | HDAC4 | Yes | Yes | 9759 | P56524 |
| TVIS30052631 | HIV | ENSG00000068024.18 | protein_coding | HDAC4 | Yes | Yes | 9759 | P56524 |
| TVIS30052632 | HIV | ENSG00000068024.18 | protein_coding | HDAC4 | Yes | Yes | 9759 | P56524 |
| TVIS30052633 | HIV | ENSG00000068024.18 | protein_coding | HDAC4 | Yes | Yes | 9759 | P56524 |
| TVIS30052634 | HIV | ENSG00000068024.18 | protein_coding | HDAC4 | Yes | Yes | 9759 | P56524 |
| TVIS30052635 | HIV | ENSG00000068024.18 | protein_coding | HDAC4 | Yes | Yes | 9759 | P56524 |
| TVIS30052636 | HIV | ENSG00000068024.18 | protein_coding | HDAC4 | Yes | Yes | 9759 | P56524 |
| TVIS30052637 | HIV | ENSG00000068024.18 | protein_coding | HDAC4 | Yes | Yes | 9759 | P56524 |
| TVIS30052638 | HIV | ENSG00000068024.18 | protein_coding | HDAC4 | Yes | Yes | 9759 | P56524 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | HDAC4 |
|---|---|
| DrugBank ID | DB06176 |
| Drug Name | Romidepsin |
| Target ID | BE0003523 |
| UniProt ID | P56524 |
| Regulation Type | inhibitor |
| PubMed IDs | 21587264 |
| Citations | VanderMolen KM, McCulloch W, Pearce CJ, Oberlies NH: Romidepsin (Istodax, NSC 630176, FR901228, FK228, depsipeptide): a natural product recently approved for cutaneous T-cell lymphoma. J Antibiot (Tokyo). 2011 Aug;64(8):525-31. doi: 10.1038/ja.2011.35. Epub 2011 May 18. |
| Groups | Approved; Investigational |
| Direct Classification | |
| SMILES | CC=C1/NC(=O)[C@H]2CSSCCC=C[C@H](CC(=O)N[C@H](C(C)C)C(=O)N2)OC(=O)[C@@H](NC1=O)C(C)C |
| Pathways | |
| PharmGKB | PA166161306 |
| ChEMBL | CHEMBL343448 |
