| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30014939 | HIV | ENSG00000161638.11 | protein_coding | ITGA5 | No | No | 3678 | P08648 |
| TVIS30014940 | HIV | ENSG00000161638.11 | protein_coding | ITGA5 | No | No | 3678 | P08648 |
| TVIS30033082 | HIV | ENSG00000161638.11 | protein_coding | ITGA5 | No | No | 3678 | P08648 |
| TVIS30033083 | HIV | ENSG00000161638.11 | protein_coding | ITGA5 | No | No | 3678 | P08648 |
| TVIS20035074 | HPV | ENSG00000161638.11 | protein_coding | ITGA5 | No | No | 3678 | P08648 |
| TVIS44050991 | HTLV-1 | ENSG00000161638.11 | protein_coding | ITGA5 | No | No | 3678 | P08648 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ITGA5 |
|---|---|
| DrugBank ID | DB08834 |
| Drug Name | Tauroursodeoxycholic acid |
| Target ID | BE0008988 |
| UniProt ID | P08648 |
| Regulation Type | activator |
| PubMed IDs | 24891994; 23456677 |
| Citations | Vang S, Longley K, Steer CJ, Low WC: The Unexpected Uses of Urso- and Tauroursodeoxycholic Acid in the Treatment of Non-liver Diseases. Glob Adv Health Med. 2014 May;3(3):58-69. doi: 10.7453/gahmj.2014.017.@@Beuers U: beta1 integrin is a long-sought sensor for tauroursodeoxycholic acid. Hepatology. 2013 Mar;57(3):867-9. doi: 10.1002/hep.26228. |
| Groups | Approved; Investigational |
| Direct Classification | Taurinated bile acids and derivatives |
| SMILES | [H][C@@]12CC[C@H]([C@H](C)CCC(=O)NCCS(O)(=O)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])[C@@H](O)C[C@]2([H])C[C@H](O)CC[C@]12C |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL272427 |
