| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44024476 | HTLV-1 | ENSG00000143473.14 | protein_coding | KCNH1 | No | No | 3756 | O95259 |
| TVIS44012409 | HTLV-1 | ENSG00000143473.14 | protein_coding | KCNH1 | No | No | 3756 | O95259 |
| TVIS44000915 | HTLV-1 | ENSG00000143473.14 | protein_coding | KCNH1 | No | No | 3756 | O95259 |
| TVIS44044018 | HTLV-1 | ENSG00000143473.14 | protein_coding | KCNH1 | No | No | 3756 | O95259 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | KCNH1 |
|---|---|
| DrugBank ID | DB00637 |
| Drug Name | Astemizole |
| Target ID | BE0005191 |
| UniProt ID | O95259 |
| Regulation Type | |
| PubMed IDs | 15365094 |
| Citations | Garcia-Ferreiro RE, Kerschensteiner D, Major F, Monje F, Stuhmer W, Pardo LA: Mechanism of block of hEag1 K+ channels by imipramine and astemizole. J Gen Physiol. 2004 Oct;124(4):301-17. Epub 2004 Sep 13. |
| Groups | Approved; Withdrawn |
| Direct Classification | Benzimidazoles |
| SMILES | COC1=CC=C(CCN2CCC(CC2)NC2=NC3=CC=CC=C3N2CC2=CC=C(F)C=C2)C=C1 |
| Pathways | Astemizole H1-Antihistamine Action |
| PharmGKB | PA448498 |
| ChEMBL | CHEMBL296419 |
