| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44043653 | HTLV-1 | ENSG00000082482.14 | protein_coding | KCNK2 | No | No | 3776 | O95069 Q6ZW95 U3N6F0 U3N834 |
| TVIS44044002 | HTLV-1 | ENSG00000082482.14 | protein_coding | KCNK2 | No | No | 3776 | O95069 Q6ZW95 U3N6F0 U3N834 |
| TVIS44043652 | HTLV-1 | ENSG00000082482.14 | protein_coding | KCNK2 | No | No | 3776 | O95069 Q6ZW95 U3N6F0 U3N834 |
| TVIS44037142 | HTLV-1 | ENSG00000082482.14 | protein_coding | KCNK2 | No | No | 3776 | O95069 Q6ZW95 U3N6F0 U3N834 |
| TVIS44035345 | HTLV-1 | ENSG00000082482.14 | protein_coding | KCNK2 | No | No | 3776 | O95069 Q6ZW95 U3N6F0 U3N834 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | KCNK2 |
|---|---|
| DrugBank ID | DB04855 |
| Drug Name | Dronedarone |
| Target ID | BE0000210 |
| UniProt ID | O95069 |
| Regulation Type | inhibitor |
| PubMed IDs | 22790794; 23997577 |
| Citations | Schmidt C, Wiedmann F, Schweizer PA, Becker R, Katus HA, Thomas D: Novel electrophysiological properties of dronedarone: inhibition of human cardiac two-pore-domain potassium (K2P) channels. Naunyn Schmiedebergs Arch Pharmacol. 2012 Oct;385(10):1003-16. doi: 10.1007/s00210-012-0780-9. Epub 2012 Jul 13.@@Heijman J, Heusch G, Dobrev D: Pleiotropic effects of antiarrhythmic agents: dronedarone in the treatment of atrial fibrillation. Clin Med Insights Cardiol. 2013 Aug 11;7:127-40. doi: 10.4137/CMC.S8445. eCollection 2013. |
| Groups | Approved |
| Direct Classification | Aryl-phenylketones |
| SMILES | CCCCN(CCCC)CCCOC1=CC=C(C=C1)C(=O)C1=C(CCCC)OC2=C1C=C(NS(C)(=O)=O)C=C2 |
| Pathways | |
| PharmGKB | PA153619853 |
| ChEMBL | CHEMBL184412 |
