Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10002063HBVENSG00000074695.6protein_codingLMAN1NoNo3998P49257
TVIS10004208HBVENSG00000074695.6protein_codingLMAN1NoNo3998P49257
TVIS10023231HBVENSG00000074695.6protein_codingLMAN1NoNo3998P49257
TVIS10028120HBVENSG00000074695.6protein_codingLMAN1NoNo3998P49257
TVIS10051666HBVENSG00000074695.6protein_codingLMAN1NoNo3998P49257
TVIS10051674HBVENSG00000074695.6protein_codingLMAN1NoNo3998P49257
TVIS30007334HIVENSG00000074695.6protein_codingLMAN1NoNo3998P49257
TVIS30046704HIVENSG00000074695.6protein_codingLMAN1NoNo3998P49257
TVIS44034811HTLV-1ENSG00000074695.6protein_codingLMAN1NoNo3998P49257
TCGA Plot Options
Drug Information
GeneLMAN1
DrugBank IDDB13998
Drug NameLonoctocog alfa
Target IDBE0002119
UniProt IDP49257
Regulation Typechaperone
PubMed IDs17139284; 17016423; 14629470; 14726380
CitationsOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Cunningham MA, Pipe SW, Zhang B, Hauri HP, Ginsburg D, Kaufman RJ: LMAN1 is a molecular chaperone for the secretion of coagulation factor VIII. J Thromb Haemost. 2003 Nov;1(11):2360-7.@@Miao HZ, Sirachainan N, Palmer L, Kucab P, Cunningham MA, Kaufman RJ, Pipe SW: Bioengineering of coagulation factor VIII for improved secretion. Blood. 2004 May 1;103(9):3412-9. Epub 2004 Jan 15.
GroupsApproved; Investigational
Direct Classification
SMILES
Pathways
PharmGKB
ChEMBL