| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10034247 | HBV | ENSG00000123384.14 | protein_coding | LRP1 | No | No | 4035 | Q07954 |
| TVIS10020853 | HBV | ENSG00000123384.14 | protein_coding | LRP1 | No | No | 4035 | Q07954 |
| TVIS30076961 | HIV | ENSG00000123384.14 | protein_coding | LRP1 | No | No | 4035 | Q07954 |
| TVIS30081785 | HIV | ENSG00000123384.14 | protein_coding | LRP1 | No | No | 4035 | Q07954 |
| TVIS30087045 | HIV | ENSG00000123384.14 | protein_coding | LRP1 | No | No | 4035 | Q07954 |
| TVIS30033297 | HIV | ENSG00000123384.14 | protein_coding | LRP1 | No | No | 4035 | Q07954 |
| TVIS30033298 | HIV | ENSG00000123384.14 | protein_coding | LRP1 | No | No | 4035 | Q07954 |
| TVIS20033436 | HPV | ENSG00000123384.14 | protein_coding | LRP1 | No | No | 4035 | Q07954 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | LRP1 |
|---|---|
| DrugBank ID | DB00031 |
| Drug Name | Tenecteplase |
| Target ID | BE0002110 |
| UniProt ID | Q07954 |
| Regulation Type | |
| PubMed IDs | 8344937; 1378833; 16303771 |
| Citations | Moestrup SK, Nielsen S, Andreasen P, Jorgensen KE, Nykjaer A, Roigaard H, Gliemann J, Christensen EI: Epithelial glycoprotein-330 mediates endocytosis of plasminogen activator-plasminogen activator inhibitor type-1 complexes. J Biol Chem. 1993 Aug 5;268(22):16564-70.@@Nykjaer A, Petersen CM, Moller B, Jensen PH, Moestrup SK, Holtet TL, Etzerodt M, Thogersen HC, Munch M, Andreasen PA, et al.: Purified alpha 2-macroglobulin receptor/LDL receptor-related protein binds urokinase.plasminogen activator inhibitor type-1 complex. Evidence that the alpha 2-macroglobulin receptor mediates cellular degradation of urokinase receptor-bound complexes. J Biol Chem. 1992 Jul 25;267(21):14543-6.@@Hu K, Yang J, Tanaka S, Gonias SL, Mars WM, Liu Y: Tissue-type plasminogen activator acts as a cytokine that triggers intracellular signal transduction and induces matrix metalloproteinase-9 gene expression. J Biol Chem. 2006 Jan 27;281(4):2120-7. Epub 2005 Nov 22. |
| Groups | Approved |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | Tenecteplase Action Pathway |
| PharmGKB | PA164776757 |
| ChEMBL | CHEMBL2108791 |
