| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30011005 | HIV | ENSG00000146701.12 | protein_coding | MDH2 | No | No | 4191 | G3XAL0 P40926 |
| TVIS20061540 | HPV | ENSG00000146701.12 | protein_coding | MDH2 | No | No | 4191 | G3XAL0 P40926 |
| TVIS44045576 | HTLV-1 | ENSG00000146701.12 | protein_coding | MDH2 | No | No | 4191 | G3XAL0 P40926 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | MDH2 |
|---|---|
| DrugBank ID | DB04272 |
| Drug Name | Citric acid |
| Target ID | BE0000780 |
| UniProt ID | P40926 |
| Regulation Type | |
| PubMed IDs | 10592235 |
| Citations | Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
| Groups | Approved; Nutraceutical; Vet_approved |
| Direct Classification | Tricarboxylic acids and derivatives |
| SMILES | OC(=O)CC(O)(CC(O)=O)C(O)=O |
| Pathways | Mitochondrial Complex II Deficiency; Congenital Lactic Acidosis; 2-Ketoglutarate Dehydrogenase Complex Deficiency; The Oncogenic Action of Succinate; Citric Acid Cycle; The Oncogenic Action of D-2-Hydroxyglutarate in Hydroxygluaricaciduria; Transfer of Acetyl Groups into Mitochondria; Glutaminolysis and Cancer; The Oncogenic Action of L-2-Hydroxyglutarate in Hydroxygluaricaciduria; Pyruvate Dehydrogenase Deficiency (E2); The Oncogenic Action of 2-Hydroxyglutarate; Fumarase Deficiency; Pyruvate Dehydrogenase Deficiency (E3); Warburg Effect; The Oncogenic Action of Fumarate |
| PharmGKB | PA449021 |
| ChEMBL | CHEMBL1261 |
