| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30085937 | HIV | ENSG00000244005.13 | protein_coding | NFS1 | No | No | 9054 | Q9Y697 |
| TVIS30053519 | HIV | ENSG00000244005.13 | protein_coding | NFS1 | No | No | 9054 | Q9Y697 |
| TVIS30053520 | HIV | ENSG00000244005.13 | protein_coding | NFS1 | No | No | 9054 | Q9Y697 |
| TVIS20055645 | HPV | ENSG00000244005.13 | protein_coding | NFS1 | No | No | 9054 | Q9Y697 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | NFS1 |
|---|---|
| DrugBank ID | DB00151 |
| Drug Name | Cysteine |
| Target ID | BE0000151 |
| UniProt ID | Q9Y697 |
| Regulation Type | |
| PubMed IDs | 17469805; 15985427; 15828873; 16877383; 16603772 |
| Citations | You D, Wang L, Yao F, Zhou X, Deng Z: A novel DNA modification by sulfur: DndA is a NifS-like cysteine desulfurase capable of assembling DndC as an iron-sulfur cluster protein in Streptomyces lividans. Biochemistry. 2007 May 22;46(20):6126-33. Epub 2007 May 1.@@Ding H, Harrison K, Lu J: Thioredoxin reductase system mediates iron binding in IscA and iron delivery for the iron-sulfur cluster assembly in IscU. J Biol Chem. 2005 Aug 26;280(34):30432-7. Epub 2005 Jun 28.@@Ding B, Smith ES, Ding H: Mobilization of the iron centre in IscA for the iron-sulphur cluster assembly in IscU. Biochem J. 2005 Aug 1;389(Pt 3):797-802.@@Yang J, Bitoun JP, Ding H: Interplay of IscA and IscU in biogenesis of iron-sulfur clusters. J Biol Chem. 2006 Sep 22;281(38):27956-63. Epub 2006 Jul 27.@@Layer G, Ollagnier-de Choudens S, Sanakis Y, Fontecave M: Iron-sulfur cluster biosynthesis: characterization of Escherichia coli CYaY as an iron donor for the assembly of [2Fe-2S] clusters in the scaffold IscU. J Biol Chem. 2006 Jun 16;281(24):16256-63. Epub 2006 Apr 9. |
| Groups | Approved; Nutraceutical |
| Direct Classification | Cysteine and derivatives |
| SMILES | N[C@@H](CS)C(O)=O |
| Pathways | Amiloride Action Pathway; gamma-Glutamyltranspeptidase Deficiency; 4-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency; Hydroflumethiazide Action Pathway; Bumetanide Action Pathway; Polythiazide Action Pathway; Ethacrynic Acid Action Pathway; Cyclothiazide Action Pathway; Trichlormethiazide Action Pathway; gamma-Glutamyltransferase Deficiency; Methionine Adenosyltransferase Deficiency; Glutamate Metabolism; Chlorothiazide Action Pathway; Pantothenate and CoA Biosynthesis; Non-Ketotic Hyperglycinemia; 2-Hydroxyglutric Aciduria (D and L Form); Indapamide Action Pathway; Hyperinsulinism-Hyperammonemia Syndrome; Iminoglycinuria; Taurine and Hypotaurine Metabolism; Glycine and Serine Metabolism; Chlorthalidone Action Pathway; Bendroflumethiazide Action Pathway; Methionine Metabolism; Eplerenone Action Pathway; Cystathionine beta-Synthase Deficiency; Glucose Transporter Defect (SGLT2); Spironolactone Action Pathway; Sarcosinemia; Quinethazone Action Pathway |
| PharmGKB | PA449173 |
| ChEMBL | CHEMBL863 |
