| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10037502 | HBV | ENSG00000114054.14 | protein_coding | PCCB | No | No | 5096 | P05166 |
| TVIS10035945 | HBV | ENSG00000114054.14 | protein_coding | PCCB | No | No | 5096 | P05166 |
| TVIS30078847 | HIV | ENSG00000114054.14 | protein_coding | PCCB | No | No | 5096 | P05166 |
| TVIS30087830 | HIV | ENSG00000114054.14 | protein_coding | PCCB | No | No | 5096 | P05166 |
| TVIS30087535 | HIV | ENSG00000114054.14 | protein_coding | PCCB | No | No | 5096 | P05166 |
| TVIS30085016 | HIV | ENSG00000114054.14 | protein_coding | PCCB | No | No | 5096 | P05166 |
| TVIS30058438 | HIV | ENSG00000114054.14 | protein_coding | PCCB | No | No | 5096 | P05166 |
| TVIS30058439 | HIV | ENSG00000114054.14 | protein_coding | PCCB | No | No | 5096 | P05166 |
| TVIS20044022 | HPV | ENSG00000114054.14 | protein_coding | PCCB | No | No | 5096 | P05166 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PCCB |
|---|---|
| DrugBank ID | DB00161 |
| Drug Name | Valine |
| Target ID | BE0000544 |
| UniProt ID | P05166 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 12409268 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Kim SN, Ryu KH, Lee EH, Kim JS, Hahn SH: Molecular analysis of PCCB gene in Korean patients with propionic acidemia. Mol Genet Metab. 2002 Nov;77(3):209-16. |
| Groups | Approved; Nutraceutical |
| Direct Classification | Valine and derivatives |
| SMILES | CC(C)[C@H](N)C(O)=O |
| Pathways | 3-Methylglutaconic Aciduria Type I; beta-Ketothiolase Deficiency; Demeclocycline Action Pathway; Josamycin Action Pathway; Gentamicin Action Pathway; Lincomycin Action Pathway; Isobutyryl-CoA Dehydrogenase Deficiency; Methacycline Action Pathway; Malonic Aciduria; Clarithromycin Action Pathway; Minocycline Action Pathway; Paromomycin Action Pathway; Lymecycline Action Pathway; 2-Methyl-3-hydroxybutryl-CoA Dehydrogenase Deficiency; 3-Hydroxy-3-methylglutaryl-CoA Lyase Deficiency; Propanoate Metabolism; Troleandomycin Action Pathway; Amikacin Action Pathway; Methylmalonic Aciduria; Oxytetracycline Action Pathway; Tetracycline Action Pathway; Spectinomycin Action Pathway; Doxycycline Action Pathway; Telithromycin Action Pathway; Roxithromycin Action Pathway; Tigecycline Action Pathway; Valine, Leucine, and Isoleucine Degradation; Arbekacin Action Pathway; Isovaleric Acidemia; Chloramphenicol Action Pathway |
| PharmGKB | PA451843 |
| ChEMBL | CHEMBL43068 |
