| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20033805 | HPV | ENSG00000078142.14 | protein_coding | PIK3C3 | No | No | 5289 | A8MYT4 Q8NEB9 |
| TVIS44007240 | HTLV-1 | ENSG00000078142.14 | protein_coding | PIK3C3 | No | No | 5289 | A8MYT4 Q8NEB9 |
| TVIS44005245 | HTLV-1 | ENSG00000078142.14 | protein_coding | PIK3C3 | No | No | 5289 | A8MYT4 Q8NEB9 |
| TVIS44042418 | HTLV-1 | ENSG00000078142.14 | protein_coding | PIK3C3 | No | No | 5289 | A8MYT4 Q8NEB9 |
| TVIS44042469 | HTLV-1 | ENSG00000078142.14 | protein_coding | PIK3C3 | No | No | 5289 | A8MYT4 Q8NEB9 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PIK3C3 |
|---|---|
| DrugBank ID | DB11962 |
| Drug Name | GSK-1059615 |
| Target ID | BE0003729 |
| UniProt ID | Q8NEB9 |
| Regulation Type | inhibitor |
| PubMed IDs | 32610557 |
| Citations | Yang CY, Liu CR, Chang IY, OuYang CN, Hsieh CH, Huang YL, Wang CI, Jan FW, Wang WL, Tsai TL, Liu H, Tseng CP, Chang YS, Wu CC, Chang KP: Cotargeting CHK1 and PI3K Synergistically Suppresses Tumor Growth of Oral Cavity Squamous Cell Carcinoma in Patient-Derived Xenografts. Cancers (Basel). 2020 Jun 29;12(7). pii: cancers12071726. doi: 10.3390/cancers12071726. |
| Groups | Investigational |
| Direct Classification | Bipyridines and oligopyridines |
| SMILES | O=C1NC(=O)C(S1)=CC1=CC=C2N=CC=C(C3=CC=NC=C3)C2=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL3544966 |
