Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10049946HBVENSG00000005421.9protein_codingPON1NoNo5444P27169
TVIS30081709HIVENSG00000005421.9protein_codingPON1NoNo5444P27169
TCGA Plot Options
Drug Information
GenePON1
DrugBank IDDB01327
Drug NameCefazolin
Target IDBE0000930
UniProt IDP27169
Regulation Typeinhibitor
PubMed IDs16600468
CitationsSinan S, Kockar F, Arslan O: Novel purification strategy for human PON1 and inhibition of the activity by cephalosporin and aminoglikozide derived antibiotics. Biochimie. 2006 May;88(5):565-74. Epub 2006 Jan 19.
GroupsApproved
Direct ClassificationCephalosporins
SMILES[H][C@]12SCC(CSC3=NN=C(C)S3)=C(N1C(=O)[C@H]2NC(=O)CN1C=NN=N1)C(O)=O
Pathways
PharmGKBPA448839
ChEMBLCHEMBL1435