| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS42001359 | EBV | ENSG00000050628.21 | protein_coding | PTGER3 | No | No | 5733 | O00325 P43115 |
| TVIS30011273 | HIV | ENSG00000050628.21 | protein_coding | PTGER3 | No | No | 5733 | O00325 P43115 |
| TVIS30005264 | HIV | ENSG00000050628.21 | protein_coding | PTGER3 | No | No | 5733 | O00325 P43115 |
| TVIS30084972 | HIV | ENSG00000050628.21 | protein_coding | PTGER3 | No | No | 5733 | O00325 P43115 |
| TVIS30083069 | HIV | ENSG00000050628.21 | protein_coding | PTGER3 | No | No | 5733 | O00325 P43115 |
| TVIS30024050 | HIV | ENSG00000050628.21 | protein_coding | PTGER3 | No | No | 5733 | O00325 P43115 |
| TVIS30024051 | HIV | ENSG00000050628.21 | protein_coding | PTGER3 | No | No | 5733 | O00325 P43115 |
| TVIS30024052 | HIV | ENSG00000050628.21 | protein_coding | PTGER3 | No | No | 5733 | O00325 P43115 |
| TVIS30024053 | HIV | ENSG00000050628.21 | protein_coding | PTGER3 | No | No | 5733 | O00325 P43115 |
| TVIS30024054 | HIV | ENSG00000050628.21 | protein_coding | PTGER3 | No | No | 5733 | O00325 P43115 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PTGER3 |
|---|---|
| DrugBank ID | DB00905 |
| Drug Name | Bimatoprost |
| Target ID | BE0002375 |
| UniProt ID | P43115 |
| Regulation Type | agonist |
| PubMed IDs | 14733708; 19232013; 16877408 |
| Citations | Sharif NA, Kelly CR, Crider JY, Williams GW, Xu SX: Ocular hypotensive FP prostaglandin (PG) analogs: PG receptor subtype binding affinities and selectivities, and agonist potencies at FP and other PG receptors in cultured cells. J Ocul Pharmacol Ther. 2003 Dec;19(6):501-15.@@Gabelt BT, Hennes EA, Bendel MA, Constant CE, Okka M, Kaufman PL: Prostaglandin subtype-selective and non-selective IOP-lowering comparison in monkeys. J Ocul Pharmacol Ther. 2009 Feb;25(1):1-8. doi: 10.1089/jop.2008.0089.@@Ota T, Aihara M, Saeki T, Narumiya S, Araie M: The effects of prostaglandin analogues on prostanoid EP1, EP2, and EP3 receptor-deficient mice. Invest Ophthalmol Vis Sci. 2006 Aug;47(8):3395-9. |
| Groups | Approved; Investigational |
| Direct Classification | Prostaglandins and related compounds |
| SMILES | CCNC(=O)CCCC=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1C=C[C@@H](O)CCC1=CC=CC=C1 |
| Pathways | |
| PharmGKB | PA164748867 |
| ChEMBL | CHEMBL1200963 |
